In fact, researchers have looked into using Zetia to treat hair loss due to a condition called alopecia areata. While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. Lipitor is also FDA-approved for the following conditions when used with a low-cholesterol diet: primary dysbetalipoproteinemia in adults (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), liver complications, such as high levels of, Both Zetia and Crestor are FDA-approved to treat the following conditions* when used with a. Crestor is also FDA-approved for the following conditions in adults when used with a low-cholesterol diet: primary dysbetalipoproteinemia (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), pain on the right side of your body, below your ribs, in adults as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin drug), in adults in combination with a fenofibrate, in combination with statins, in people with hepatic disease, in combination with statins, in people with elevated hepatic transaminases, in combination with statins, during pregnancy or in someone planning to become pregnant, in combination with statins, while breastfeeding, in people who have a known allergy to Zetia. Before starting a new medication, its a good idea to talk with a healthcare professional about any questions or concerns you may have. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. Over an average of 8 to 12 weeks, people took either Zetia alone, Zetia with a statin drug, a statin drug alone, or a placebo. What Are the Injectable Alternatives to Statins? Zetia is metabolized in the small intestine and liver. This can cause gallstones (hardened stones in your gallbladder). POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. Statins lower cholesterol by preventing your liver from making new cholesterol. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. The brand name for this drug combination is Vytorin. If you use Zetia and warfarin together, your doctor may want to monitor you more closely during your treatment. It wasnt reported during studies of the drug. If you have questions about the differences between Zetia and statin drugs, talk with your doctor. Some side effects are more common than others. Zetia is approved to treat different types of high cholesterol. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. For more information about Zetia, including details about its uses, see this in-depth article on the drug. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. If your doctor confirms you had a mild allergic reaction to Zetia, theyll decide if you should continue using it. Read more about these alternatives to traditional statin, Having high cholesterol puts you at risk for a heart attack or stroke. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. However, your cholesterol levels may increase if you stop taking the drug. (Mixed hyperlipidemia is also known as mixed high cholesterol.). A large review by the American Heart Association compared studies of CoQ10. Your child can take Zetia with or without food. They can both be taken with or without food. Covers lawsuits, malpractice, class actions, fraud, legislation, regulation, enforcement. Before trying something new, its common to look for written reviews about the experiences of others. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). In certain conditions (such as when traveling), you may temporarily store Zetia at temperatures of 59F to 86F (15C to 30C). If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. Many rare diseases have limited information. . Also, if you have a history of heavy drinking or liver damage, be sure to tell your doctor before you begin taking Zetia. In these studies, 12 weeks of treatment with Zetia and fenofibrate was compared with Zetia taken alone, fenofibrate taken alone, or a placebo (a treatment with no active drug). When this happens, more cholesterol can then be cleared from your blood by your liver. Learn about the drugs dosages, forms, strengths, and more. Both drugs are typically taken once each day. This is because every persons body responds differently to medications. Zetia may also increase the amount of cholesterol thats stored in your gallbladder. A generic drug is an exact copy of the active drug in a brand-name medication. 2. Medications in this class prevent your small intestine from absorbing cholesterol. If you miss a dose of Zetia, you can take your missed dose as soon as you remember. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Zetia may cause joint pain. Rhabdomyolysis can also occur with statin drugs, and you may need to take Zetia with a statin. You should always consult your doctor or another healthcare professional before taking any medication. Or they may recommend a product you apply to your skin, such as hydrocortisone cream. Clinical studies looked at Zetia for the treatment of primary hyperlipidemia in adults and in children ages 10 years and older. You may experience muscle problems as a side effect of Zetia. yellowing of your skin or the whites of your eyes, ahajournals.org/doi/10.1161/JAHA.118.009835, organon.com/product/usa/pi_circulars/z/zetia/zetia_pi.pdf, Alternatives to Statins for Lowering Cholesterol. If your doctor confirms you had a serious allergic reaction to Zetia, they may have you switch to a different treatment. For more information on these side effects, see Side effect details below. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. Crestor is part of the statin drug class. Porphyria patients are often overly sensitive to sunlight. If youre currently taking cyclosporine, talk with your doctor about whether its safe for you to take Zetia. These symptoms could be life threatening and require immediate medical care. A Mayo Clinic study published this month in Pacing and Electrophysiology (PACE), suggests that a class of medications more commonly prescribed for older adults is a strong first-line treatment for teenagers with a debilitating condition called postural orthostatic tachycardia syndrome, or POTS. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. More research is needed to know for sure. Cholestyramine (Prevalite) is a drug used to treat high cholesterol. Grapefruit can prevent the breakdown of these drugs in your body. (A class of drugs is a group of medications that work in a similar way.) * For more information about this side effect, see " Zetia: Side effects explained " below. Zetia is a brand-name drug that contains the active drug ezetimibe. Get medical help right away, if you have any of the symptoms listed above. Medications in the fibrate drug class are used to treat high cholesterol. For more information and to find out if youre eligible for support, call 800-727-5400 or visit the program website. For some drugs, doing so may lead to unwanted side effects or overdose. People with HoFH have high levels of LDL (bad) cholesterol. About Postural orthostatic tachycardia syndrome. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. For more information, see the How Zetia works section below. What foods should I avoid while taking Zetia. (A class of medications is a group of drugs that work in a similar way.) This includes grapefruit and grapefruit juice. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . This date is typically 1 year from the date they dispensed the medication. More common side effects in people taking Zetia* include: * In studies, these side effects were reported in people who took Zetia by itself. They may be able to suggest ways to relieve this side effect. You may also be having a reaction to all the medications mixed together. They may have suggestions depending on your weight and health goals. stuffy nose. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. Your doctor will likely start you on the typical dosage approved to treat your condition. But it may be a sign that your liver isnt working as well as it should. Postural Orthostatic Tachycardia Syndrome (POTS) is a blood flow disorder that causes a sudden spike in heartbeat with no change in blood pressure when going from a horizontal or seated to a standing position. tightness of chest or wheezing. It's Aimee Esther here! Have your doctor measure your heart rate sitting and standing. diarrhea*. For instance, some interactions can interfere with how well a drug works. POTS is commonly associated with low levels of fluid. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. Talk with your doctor about any liver problems you may have and whether its safe for you to take Zetia. And generics tend to cost less than brand-name drugs. Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain. New evidence shows that the drug makers Merck and Schering-Plough have conducted several studies of their popular cholesterol medicine Zetia that raise questions about its risks to the liver, but . Ezetimibe can cause the breakdown of muscle tissue . Most of Zetias side effects should go away within a few days or weeks. Zetia is also used to reduce blood levels of fats called plant sterols in people with homozygous sitosterolemia. Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug) and Zetia is a cholesterol -lowering drug. This is because large meals can cause blood to pool excessively in the abdomen. Do my other medications increase my risk of side effects with Zetia? Zetia contains the active drug ezetimibe. Therefore, you shouldnt breastfeed if youre taking Zetia with a statin drug. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate. Zetia comes as a tablet that you swallow. Allergic reaction. Theyll guide you on the safest treatment options for you. In most cases, these side effects should be temporary. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. In studies, some people had to stop taking Zetia because of this side effect. This is because fenofibrate is the only fibrate Zetia was studied with, so it isnt known whether Zetia and other fibrate drugs are safe to use together. They may want to select a different treatment option for you. Its primary metabolic pathway is via hepatic glucuronic conjunction. Based on animal studies, Zetia may cause harm to the fetus when taken by a pregnant woman. Zetia contains the active drug ezetimibe. Forget HDL and LDL. Examples of bile acid sequestrants include: Zetia inhibits the intestinal absorption of cholesterol and phytosterols, resulting in a decrease in the transport of intestinal cholesterol to the liver. Also occur with statin drugs include atorvastatin ( Lipitor ) and simvastatin ( Zocor.... Planning to breastfeed while taking Zetia, this may be an explanation for any weight loss may! 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