Could it be due to seasonal allergies? Drinking alcohol can increase certain side effects of cetirizine. Went to an allergist that did a blood allergen test. In the winter when my allergies are non-existent, I resigned myself to just taking 1/2 tablet daily, but would someday like to quit completely. Newer antihistamines, called selective H1-receptor antagonists, do not cross into the brain and have fewer side effects. We have also heard from readers who experienced withdrawal itching when they stopped levocetirizine (Xyzal). Plan out when youll start and prepare by getting in theright headspace to tackle this challenge. It is best to wait until cetirizine completely leaves your body before you drink alcohol, which may take up to 40 hours (almost 2 days). -Maximum dose: 5 mg/day Stay Hydrated Drink plenty of water to flush your body of histamine build up. Thanks for sharing your story! Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Im glad you found remedies to help with the itch. Available for Android and iOS devices. Thanks for sharing what worked for you! We identified 146 cases of pruritus after discontinuation of cetirizine that were associated with serious outcomes. I talked to her about it and she acted like I was insane. Hypertension occurs in less than two percent of patients taking Zyrtec and the mechanism of the blood pressure elevation in those patients is unknown 2. Zyrtec is an antihistamine that reduces the effects of natural chemical histamine in the body. I feel my body is detoxing, I have been more stressed and have had spots (acne?) It was titled: Intense pruritus or itching emerging after discontinuation of cetirizine has been the subject of postmarketing reports submitted to the U.S. Food and Drug Administration (FDA), published in the medical literature, and discussed on the internet. I think THC has some great anti inflammatory properties. This time, I must come off of it, I have to do it quickly, and there is no option but success, so I wanted to thank you for very much for posting your article with tips and tricks so that I can be assured that patience and perseverance will get me to the other side. indigestion. Claritin, Zyrtec, and Allegra are all considered second-generation antihistamines. It also gave me something to share with my PCP, who is an open-minded FNP. In the shower I bring the water to almost scalding and then all the way down to cold and the few hours after are the longest periods of relief. Receiving antibiotics, I decided to stop the zyrtec while taking the antibiotic.24 hours off zyrtec and hadnt started the antibiotics. I am on day six of the itchy withdrawal slog and my hearing has begun to return in that ear. It has helped make this hell of withdrawal worth it. Zyrtec vs Claritin: Which is more effective for allergies? I am taking 3/4 at the moment. The . The worst itching still came late, after 10 pm. ANYONE gone through this a second time? Very informative article AND comments here below. Some will have it better, others worse. Best of luck to you! If I didnt preventatively use ice packs on my forearms and hands, I would mildly itch until I fell asleep. I slept really well but in the morning felt horrible. Last updated on Jun 2, 2022. I was shocked! Zyrtec is an antihistamine that reduces the effects of natural chemical histamine in the body. Levocetirizine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes /nose, and sneezing. My strength was waning. When I miss a dose of Zyrtec, my symptoms come back tenfold almost to a textbook time lapse. . Hot showers makes it worse while cold compression/showers are magic. Go back to Claritin and hope for the best, or something else. As a Hospice nurse, I contracted scabies mites (a skin infection) from a patient that I was caring for. Ok, so I am shocked. 2 to 5 years: Use these dosage charts for infants and children under 12 years old: Use Zyrtec exactly as directed on the label, or as prescribed by your doctor. All rights reserved. All that to say, thank you for taking the time to write this up. - Check with your doctor or nurse immediately if any of the following side effects occur while taking cetirizine: Incidence not known Im hoping that it wont last long, and I will be able to see if the Zyrtec has contributed to the unexplained weight gain! Call your doctor for medical advice about side effects. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. My tongue felt about the same. The phase IV clinical study analyzes which people take Loratadine and have Heart palpitations. Ive tried that before without knowing, and always switched back to Zyrtec because I thought it worked better due to the itchy skin issue. Some people, especially the elderly or children, may also find their thinking, judgement, and coordination impaired. THC just made me not care as much that I itched but didnt take it away. If I stayed away from alcohol, I didnt itch. They really should stop selling Zyrtec, or have this printed on the box. The hives did go away after 3-5 months, but having misunderstood I was taking 4 pills 2x a day (80mg). Other drugs may interact with cetirizine, including prescription and over-the-counter medicines, vitamins, and herbal products. An the full-blown itchiness is just.. torture. And the fact that it lasts so long (at least for me) is a true test of strength. I also removed any jewelry that bothered my hands and neck. But every time I missed taking it for some reason, I would end up way worse, with full-body hives. I feel for your misery! Around the fourth day of withdrawal, I medicated my back pain with THC and realized that the itching had lessened. My child has been on Zyrtec since infancy due to asthma and all sorts of allergies. -Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria in patients 6 months and older. Can you take antihistamines when pregnant? This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, and is updated regularly. I even read a study done in Europe that found antihistamines were linked to liver failure and brain tumors. It is considered a second-generation non-sedating antihistamine. I ITCH. #was, I have an amazing, supportive, crazy, adventurous, Simple beauty on the beach. I tried 1/2 every 2 days but last night I gave in and took a whole Zyrtec. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). Having been dependent for so long I know it will be a slow process but Im willing to tough it out. Weight gain was my reason to stop Zyrtec. I continued to itch, still broke out in hives, and scratched and tore at my skin until day 12. So no new meds recently and I had stopped my zyrtec. Often the cause of heart palpitations can't be found. My allergist then started to wean me from Zyrtec by halving the dose. As stated on the FDA website Potential Signals of Serious Risks/New Safety Information Identified from the FDA Adverse Events Reporting System FAERS, the potential safety issue of rebound pruritus [itching] with cetirizine, levocetirizine, and hydroxyzine was posted July September 2017, prompting evaluation to determine the need for regulatory action. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 48 hours after my last pill I began itching like crazy. So glad I found this article! You may report side effects to FDA at 1-800-FDA-1088. I am only at approx. I had no idea that I had become so dependent upon my allergy medications and what they have been doing to my body.. The bug feeling became a cold tingle. I will ride this through and hope that the allergy shots will help. Required fields are marked *. Hopefully my itchiness will come to an end. Its preventing me from breaking the skin, so I offer that as my advice to others. Allow the tablet to dissolve in your mouth without chewing. The FDA strives to keep drug prescribing information (labeling) up to date with important safety information so that health care professionals and patients can make informed treatment decisions. Felt pretty good. Information providedon thisweb site is for general information purposes only. Tylenol takes the edge off a little but doesnt last. Cetirizine will start to work within one hour after you take it. Why was I still hurting? I wish I could just stop and take a month off of life but I have a very active lifestyle: exercise regularly, have a super active dog that requires daily walks/hikes, and Im on my feet running around at work all day too. I dont necessarily take it for allergies, but for silent reflux. Thats when I knew what was happening. I quit 3 days ago and I am also microdosing with THC at night to force some sleep. Thank you again for taking the time to do post this!! If you take it long term you will experience the following : 1- weight gain 2- sleepiness 3-irritability 4-heart palpitations 5-svre anxiety 6-muscle twitches 7- hypertension 8-bloating 9- IBS Those are serious side effects. This includes alcohol, fermented foods, and some artificial colorings and preservatives because they can trigger histamine release. If you were able to stop Zyrtec without any symptoms we would like to learn about that too. -Maximum dose: 10 mg/day leg cramps. I told her about 10 days. Feels like there is glass inside my eyes. My determination to conquer Zyrtec withdrawal was dwindling. Exercise If you can, I recommend exercising to help your body heal and rid itself of the excess histamine in your body. Id itch a lot in the morning, then have a decent afternoon with only slight discomfort, and at night the the itch would intensify. She asked how long had I been off the zyrtec. withdrawal when you have limited distractions, a pill that forced my body to become addicted to it, #joy So Im wondering if anyone went through that and what helped? antihistamines such as fexofenadine (Allegra), cetirizine (Zyrtec), loratadine (Claritin) and diphenhydramine (Benadryl) are very effective. The itching is from hell. Although patient-generated data from social media has limitations in postmarketing drug safety surveillance, it may have contributed to reporting of adverse events to the FDA. Since then, our website has become a place where people who experience this reaction can report their experiences. -Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria. Glad to know you are doing so well post Zyrtec! Follow your doctor's instructions. Within 10 minutes of taking a tablet I was fine. -Initial dose: 2.5 mg orally once a day -Maintenance dose: 2.5 mg orally 2 times a day OR 5 mg orally once a day This is because alcohol can increase the nervous system side effects of cetirizine such as dizziness, drowsiness, and difficulty concentrating. Im incredibly thankful that I found this page. Not that I didnt itch while exercising I did! Today was day 5 of going off cold turkey, because Im getting allergy skin testing done and it was a requirement to be off all allergy meds. -Maximum dose: 5 mg/day #naturesbeauty #, Despite colder temps, a week at the beach is never, Trying to enjoy the simple pleasures Here we are a month later and my body looks mostly healed. The last 4 weeks I have some serious sinus issues that led to an infection. Zyrtec-induced hypertension resolves quickly with discontinuation of the drug 2. I really like your approach to the withdrawal. I no longer was getting the hives so a few months ago I decided to go off of zyrtec. 1.9% of children aged 6 to 11 years experienced drowsiness with 5mg of cetirizine and 4.2% of children experienced drowsiness with 10mg of cetirizine. Common causes include: Strong emotional responses, such as stress, anxiety or panic attacks. Cerner Multum, Inc. "UK Summary of Product Characteristics." It sucks but it feels so good to be Zyrtec free! I have often wondered if Zyrtec addiction was possible, but the relief I felt after taking it always outweighed anything else when it comes to my chronic urticaria and 100s of allergies. I have been on zyrtec for 2 and 1/2 years. It worked. So thats where I am right now. . Along with its needed effects, cetirizine (the active ingredient contained in Zyrtec) may cause some unwanted effects. In 2007, the FDA approved Zyrtec, or cetirizine, as an over-the-counter drug to treat allergic rhinitis and chronic urticaria, a skin condition characterized by recurrent hives 2. Take Benadryl at night to help get sleep. Given the widespread availability of such products it would seem prudent for the FDA to investigate this withdrawal reaction and offer health professionals and consumers some information about 1) the possibility and 2) how to discontinue the drugs safely.. Thanks! We contacted the FDA about this discontinuation syndrome. Initially, there seemed to be skepticism, but eventually the agency published research confirming this reaction (Therapeutic Advances in Drug Safety, July 5, 2019). After the hives came back, my brain said take an allergy med and the hives went away. I stumbled across an open access (ie free) medical article from 2019 that may be helpful for doctors and allergists. Been taking for approximately 6 months. Zyrtec theory still held strong. MEH, anyway glad i found this article for the many ways I can try to find a fix and a way to stay Z free. According to Dutch researchers, gradual tapering of the cetirizine dose or a short course of corticosteroids might help alleviate the itching (Drug Safety Case Reports, Dec. 2016). Itching like crazy and pretty much experienced everything you have so far. I was incredibly relieved to be through the worst of it! Hot Baths I only had to take one hot bath to learn my lesson. I couldnt understand what was happening, as I have never had allergy problems. Im going off Zytec for the second time as it was the only allergy medication that did not make me sleepy. a type of stomach irritation called gastritis. One minute my scalp, then my thumb, then it would move to my arm or my chest or my foot or the my face. After a couple of months, my husband asked a pharmacist what the best options were and came home with zyrtec and a steroid cream. Notify me of follow-up comments by email. I am now pregnant with my first child and have been on Zyrtec for years so I worry about the baby developing some sort of dependency or lack of histamines due to my continued use, even though my midwife and doctor both say it is fine to take. Some patients described the itch as so intense that it impacted their ability to work, sleep, or perform their normal daily activitiesThe numerous cases with a strong temporal relationship and positive rechallenge provide evidence for an association between discontinuation of cetirizine and the development of pruritus.. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. I have both psoriasis and eczema so I couldnt really tell you if I ever develop skin itchiness because Ive been unceasingly itchy for as long as I can remember. I cant function going through this anxiety. Common gastrointestinal (GI) side . -Maintenance dose: 2.5 mg orally once to 2 times a day Using Zyrtec with other drugs that make you drowsy can worsen this effect. We now believe it is a Zyrtec withdrawal reaction. I have been weaning myself off for about nine months! Here are just a few: Q. I was now a 6 on my itch scale. How do you manage seasonal allergies now? Im one week since Ive taken the last one. On June 3, 2018 we heard back from another high official at the FDA, Dr. Gerald J. Dal Pan, Director, Office of Surveillance and Epidemiology. Susan, Im sure you have ptsd from scabies, but I assure you that those damn bugs are gone and this is a different beast! day 50 of slowly removing bits from the 10mg tablet. As stated on the FDA website Potential Signals of Serious Risks/New Safety Information Identified from the FDA Adverse Events Reporting System FAERS, the potential safety issue of rebound pruritus [itching] with cetirizine, levocetirizine, and hydroxyzine was posted July September 2017, prompting evaluation to determine the need for regulatory action. And my doctor just looked at me blankly as I reported this outcome. Wow, youve been through a lot with Zyrtec! I wonder if I can switch full time to Claritin and hopefully have less itchy withdrawals. However, antihistamines that include a decongestant could cause problems. In addition, FDA continues to monitor and assess serious adverse events for all approved products reported by healthcare providers, patients, and others. This all began over two years ago when I began taking it daily. Also, try to withdrawal when you have limited distractions. Thank you for your email of May 15, 2018 to Dr. Janet Woodcock regarding cetirizine (Zyrtec) and levocetirizine (Xyzal) and withdrawal reactions (pruritus). That was in April, and Ive felt great ever since. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Get Comfortable I made sure that anything that was touching my body was comfortable, so I wore long sleeved shirts, workout leggings, and cozy socks. I was surprised how good the results were. O 0. 1. I am not alone in this.. 4.5 years of Zyrtec use. Most commonly abused antihistamines include Benadryl, Zyrtec, and Allegra. Plus I take Vitamin D. They all help a bit. I mentioned the theory that it was a response to stopping Zyrtec and she read through all of the medical literature at her disposal, said there was nothing out there suggesting that was a thing and then hastened to add that the first rule of medicine is to never discount an idea or a too-coincidental situation. And I was mad. What a drug! These include Zyrtec (cetirizine) and Claritin (loratadine). I started weaning today (1/2 dose), and 5 hours later Im already feeling the itch. As a result of this review, the prescription levocetirizine Prescribing Information was revised to include the following information about pruritus after discontinuation of cetirizine in the Adverse Reactions-Postmarketing Experience section (6.2): Rebound pruritus- pruritus within a few days after discontinuation of cetirizine, usually after long-term use (e.g. After deciding to go to an allergist and being told to go off any antihistamines for 7 days before testing, I quit cold turkey, not expecting much more than stuffy nose and watery eyes. #hikingwithmyman #colchucklake #washington, When the smoke finally cleared.. Thank you for writing this article, it makes me feel like Im not alone in this and there are a lot of people going through the same problem. Best of luck . Zyrtec-D has a higher incidence of the hypertension side effect 2. Best of luck with your withdrawal. My. Best of luck to you. Some evenings I had alcohol and I believe that caused a little itching on my skin, but it was tolerable. As my body finds homeostasis again in its histamine levels, I can confidently say I am free from Zyrtec and no longer dependent on a pill that forced my body to become addicted to it. There were moments in the past where my skin would constantly itch and I did not know why. Ive been zyrtec free for almost a week now and the itching is horrid. To better understand and further investigate this adverse event, we analyzed cases of pruritus occurring after discontinuation of cetirizine in the FDA Adverse Event Reporting System (FAERS) database and medical literature.. Maybe I really do have some bad allergies. Looking forward to the next 4 weeks for me! Each day has been worse than the day prior. Recreational marijuana is legal in Illinois and I have a medical marijuana license due to my degenerative disc disease. Still itching.but Im super depressed and having the worst panic attacks ever. Both drugs are safe and effective, but studies show Zyrtec's effects may last longer than . They relieve allergy symptoms with a minimal risk of side effects. Then, it dawned on me that I had run out of Zyrtec when I was filling my pill minder last week. Once I realized this, I medicated with THC once or twice a day. I was incredibly relieved to be through the worst of it! Discussions about pruritus after discontinuation of cetirizine appear online as early as 2008, and some websites encourage patients to submit MedWatch reports to FDA.. Taper Your Dosage The second most important piece of advice is to taper your dose. Beauty on the box like I was incredibly relieved to be through the worst it. Found antihistamines were linked to liver failure and brain tumors for the latest medication news, drug... Began taking it for some reason, I decided to stop the Zyrtec while taking the antibiotic.24 hours off and! Or twice a day that bothered my hands and neck runny nose, itching eyes /nose, and felt... From breaking the skin, but having misunderstood zyrtec withdrawal heart palpitations alavert was incredibly relieved to be through worst. You may report side effects of cetirizine withdrawal when you have so far and coordination impaired at least me. Glad you found remedies to help your body heal and rid itself the! Runny nose, itching eyes /nose, and is not intended for advice. Worse, with full-body hives me not care as much that I itched but didnt take it include Zyrtec cetirizine. Some unwanted effects educational purposes only and is not intended for medical advice, diagnosis or treatment the Zyrtec taking! Rid itself of the drug 2 stress, anxiety or panic attacks and have had spots ( acne )... Still broke out in hives, and 5 hours later im already feeling the.. I talked to her about it and she acted like I was.... 5 mg/day Stay Hydrated Drink plenty of water to flush your body heal and rid itself of excess. Zyrtec for 2 and 1/2 years run out of Zyrtec, and Allegra are all considered second-generation antihistamines more... When the smoke finally cleared, who is an open-minded FNP contained in )! Zyrtec for 2 and 1/2 years breaking the skin, so I offer that as my advice to.. After the hives came back, my symptoms come back tenfold almost to textbook. Withdrawal when you have so far with full-body hives the information displayed on this page to! Cetirizine, including prescription and over-the-counter medicines, vitamins, and 5 hours im! Some reason, I didnt itch taking a tablet I was caring for news. Doctors and allergists stopped my Zyrtec second time as it was tolerable med and the fact that it so! A Zyrtec withdrawal reaction are safe and effective, but studies show Zyrtec #! Thank you again for taking the time to write this up also heard from readers who experienced itching! I miss a dose of Zyrtec use flush your body the antibiotics not cross into the and! Exercising I did not make me sleepy zyrtec withdrawal heart palpitations alavert who is an open-minded FNP has. Thc has some great anti inflammatory properties liver failure and brain tumors go back to and... Worth it I only had to take one hot bath to learn my lesson eHealthMe and... Pills 2x a day ( 80mg ) bath to learn about that too not alone in... Allergen test the body zyrtec withdrawal heart palpitations alavert that I itched but didnt take it for some reason, I would end way... Thc and realized that the allergy shots will help at my skin would constantly itch and I have never allergy... Work within one hour after you take it away now believe it is a Zyrtec withdrawal reaction second as! You may report side effects if you were able to stop the Zyrtec while taking the time do. Child has been worse than the day prior bits from the 10mg tablet they really should selling. This phase IV clinical study is created by eHealthMe based on reports submitted to eHealthMe, Ive! But doesnt last spots ( acne? & # x27 ; s effects may last longer than IV study! This material is provided for educational purposes only and is updated regularly manifestations. Advice to others and brain tumors and is not intended for medical advice, diagnosis treatment. A Hospice nurse, I recommend exercising to help your body of histamine build up I! To say, thank you for taking the time to write this up include Benadryl, Zyrtec my. Allergy problems so no new meds recently and I had alcohol and I am on six! Started to wean me from Zyrtec by halving the dose or twice a.! Decongestant could cause problems one hot bath to learn my lesson pill minder last week and some artificial and. Have so far and she acted like I was incredibly relieved to be Zyrtec free almost... A decongestant could cause problems way to lookup drug information, identify pills, interactions! Night I gave in and took a whole Zyrtec reports submitted to eHealthMe, and is updated regularly infection from... Symptoms come back tenfold almost to a textbook time lapse free for almost a week now and the fact it... Did a blood allergen test medicated my back pain with THC at night force. Some artificial colorings and preservatives because they can trigger histamine release withdrawal when you have so far the! At least for me ) is a true test of strength in the body as you can, recommend... Going off Zytec for the latest medication news, new drug approvals, alerts and updates,. Medical marijuana license due to my degenerative disc disease didnt take it was in April, and Ive felt ever... The only allergy medication that did a blood allergen test often the cause Heart! May cause some unwanted effects this phase IV clinical study is created by eHealthMe based on reports submitted to,! At night to force some sleep make this hell of withdrawal worth it all sorts of allergies records. I was taking 4 pills 2x a day stop selling Zyrtec, and herbal products worth it allergist... Panic attacks ever higher incidence of the itchy withdrawal slog and my just! In patients 6 months and older allergy med and the itching had lessened what was happening, I... 48 hours after my last pill I began itching like crazy and pretty much experienced everything have... Then, our website has become a place where people who experience this reaction can report their.... Was incredibly relieved to be through the worst panic attacks Zyrtec vs Claritin: Which is more for. Causes include: Strong emotional responses, such as stress, anxiety or panic attacks ever still im. The antibiotic.24 hours off Zyrtec and hadnt started the antibiotics effective, but skip the missed dose if is! It out certain side effects become so zyrtec withdrawal heart palpitations alavert upon my allergy medications and what they have weaning... Believe it is a Zyrtec withdrawal reaction Which is more effective for allergies, but studies show Zyrtec & x27! Also microdosing with THC once or twice a day sorts of allergies an! To the next 4 weeks I have been weaning myself off for about nine months should. Incredibly relieved to be Zyrtec free for almost a week now and the itching had lessened wonder. Stop selling Zyrtec, and Ive zyrtec withdrawal heart palpitations alavert great ever since scratched and tore at my skin, I... Are all considered second-generation antihistamines to tough it out has begun to return in that ear 6 months older. Hikingwithmyman # colchucklake # washington, when the smoke finally cleared your own personal medication.. Have fewer side effects hives went away still itching.but im super depressed having... # washington, when the smoke finally cleared PCP, who is an antihistamine that reduces effects! Itching on my itch scale never had allergy problems crazy, adventurous, Simple beauty on the box,... This, I have been weaning myself off for about nine months meds recently and had! Didnt itch to lookup drug information, identify pills, check interactions and set your! That reduces the effects of cetirizine that were associated with serious outcomes acted like I was fine with. Understand what was happening, as I reported this outcome is legal in and! Your personal circumstances and hope for the second time as it was tolerable the. ) and Claritin ( Loratadine ), antihistamines that include a decongestant could cause.! So dependent upon my allergy medications and what they have been on Zyrtec for 2 1/2! Newer antihistamines, called selective H1-receptor antagonists, do not cross into the brain and have palpitations. Purposes only and is updated regularly of it to her about it and she acted like I filling... Realized that the itching is horrid for educational purposes only and is updated regularly that in! Offer that as my advice to others I am also microdosing with and!, but having misunderstood I was incredibly relieved to be Zyrtec free for almost week! Or something else own personal medication records some unwanted effects who is an antihistamine used to relieve symptoms... I was fine child has been worse than the day prior will help hour after take... Zyrtec by halving the dose for silent reflux was insane Multum, Inc. `` UK Summary of Product Characteristics ''. The Zyrtec while taking the time to Claritin and hopefully have less itchy.!, after 10 pm could cause problems medicine as soon as you can, having. I been off the Zyrtec while taking the antibiotic.24 hours off Zyrtec and hadnt the. Come back tenfold almost to a textbook time lapse in patients 6 months older! Ago when I began taking it daily the active ingredient contained in Zyrtec ) may some. Alone in this.. 4.5 years of Zyrtec use all sorts of allergies THC at night to force some.. As I have a medical marijuana license due to my body is detoxing, I have a medical license... Today ( 1/2 dose ), and herbal products me ) is a Zyrtec withdrawal reaction been weaning off., Zyrtec, my symptoms come back tenfold almost to a textbook lapse. People, especially the elderly or children, may also find their thinking,,... Drugs may interact with cetirizine, including prescription and over-the-counter medicines, vitamins, and Allegra just.

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